Glycine

Glycine is the simplest non-essential amino acid. Glycine is required for optimal growth and the synthesis of creatine. It is synthesized from dimethylglycine (DMG)

=Properties= -Component of the main calming neurotransmitters -Component of the retina -Promotes the increase of glycogen levels -Participates in DNA synthesis (purine nucleotide) -Stimulates acetylcholine -Required for the synthesis of glycerol -Required for the synthesis of phospholipids -Required for the synthesis of the conjugated proteins of cholesterol -Component of colagen and skin proteins -Component of glutathione -Detoxifying agent

=Complements= Alanine and glutamic acid (hypertrophy of the prostate)

=Antagonists= None Known

=Precursor of:= -Glutathione and collagen -Creatine -Interconversion w/ Serine

=Deficiency= Intoxication from weak phase 2 hepatic conjugation

=Therapeutic Indications= -For an increased need to detoxify the body of nitrates or benzoic and cholic acids -Cancer and other oxidizing reactions -Schizophrenia -Benign hyperplasia of the prostate (w/ alanine and glutamic acid) -Promotes glutathione synthesis -Inhibits the synthesis of cholesterol and triglycerides -Lowers cholesterol and triglyceride levels in the blood

=Contraindications= None Known

=Food Sources= -Foods w/ high protein content, such as meat, fish, legumes and nuts

=Therapeutic Dose= DMG: more than 3g./day Glycine: Food sources. Not necessary as a supplement.

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============================================================ //Medical Nutririon// GLYCINE- DMG/ TMG – Di and Tri -methylglycine -Simplest amino acid –CH2 with carboxyl and nitrate attached. • -Involved with formation of methionine, GSH, Choline, hormones and neurotransmitters • -It is a primary neurotransmitter for communication of the brain to the body. • -It helps energy, immunity and oxygen utilization • -It supports transmethylation where it helps formation and function of vitamins, neurotransmitters, enzymes, nucleic acids and antibodies. It helps make SAMe which assists in 41 transmethylation reactions

Treatment
• -Angina • -Glucose metabolism • -Athletic performance • -Blood lipids • -Blood pressure • -Brain alertness • -Autism- helps verbal communication, social interaction and improves behavior.


 * Dose:** DMG125mg-1000mg/d