Naringin

=Generalities= Naringin is found in the white pulp of bitter oranges and grapefruit

=Properties= It inhibits the iso-enzymes of cytochrome P450 of phase 1 hepatic detoxification and of intestinal cells, which decreases the body's ability to detoxify itself, particularly of medications -Antioxidant

=Therapeutic Indications= -Anti-cancerous

=Contraindications and Precautions= With medications: may increase, or less frequently decrease the effects of medications. It prevents n enzyme from metabolizing these medications, which increases their concentration in the blood thus leading to sometimes deadly side effects. A single 8 oz. glass of juice can increase the level of medication in the blood - an effect that may last 3 or more days.

=Precautions and Side Effects= Taking Medications

=Food Sources= -Bitter Orange -Grapefruit (pink or white)

=Therapeutic Dose= 15-60mg./day or 25,000-100,000 IU/day